6 Effective Vitamin Supplements For Neuropathy and Nerve Pain

When treating neuropathy and nerve pain, doctors and other medical practitioners are required to have ample knowledge of all available medicine systems that could work. Some of them have even started recommending alternatives to conventional medication and procedures after realizing that drugs and surgery may not be enough to achieve full nerve rehabilitation.


Among the popular options given to most neuropathy patients is supplementation. In fact, this has become widely considered in the field that supplement manufacturers jumped in to help relieve people suffering from nerve pain.

Nerve Renew is one of the most popular supplements available in the market. A review of this supplement on NervePainGuide.org shows that it contains several active ingredients that include fatty acids, vitamins, and minerals to help alleviate discomfort caused by nerve damage.

Below are six effective vitamin supplements for neuropathy and nerve pain.

Vitamin D

Vitamin D is known for its benefits for better calcium absorption in the bones. However, several studies have shown that neuropathic patients may also benefit from this supplement. Based on a research published in 2017 in The Journal of Clinical and Translational Endocrinology, Vitamin D deficiency is linked to painful diabetic neuropathy. While further studies need to be conducted to establish this, experts believe that it may be connected to the prevalence of inflammation and damage on the nerves.

Vitamin E

Every person needs Vitamin E in their body because it provides protection against oxidative stress and prevents cells from being damaged due to free radicals. It is also considered an essential part of neuropathy treatment as it acts by securing the protective membrane of the nerves called myelin sheaths. This part of the nerves composed of lipids serve as an insulator and boosts nerve conduction. This means myelin sheaths also play a critical role in the nerves’ function in sending and receiving signals from the brain and spinal cord.


Benfotiamine is the fat-dissolvable variant of thiamine, more commonly called as Vitamin B1. As part of the B-Complex family, Vitamin B1 is necessary for healthy nerves. However, most supplements made for neuropathy patients deliver this vitamin in the form of benfotiamine because it is metabolized by the body quite slower than its water-soluble counterpart. This means that benfotiamine is more bioavailable and, thus, more efficient in preventing nerve damage.

Alpha Lipoic Acid

Although its therapeutic effects have yet to be confirmed by most drug agencies, Alpha Lipoic acid or ALA has been widely used for neuropathy treatments, particularly for diabetic patients. This is because ALA shows great potential in protecting nerves from damage and inflammation because it is a powerful antioxidant. However, its efficacy is based on the dosage which has yet to be researched further.

Methyl B-12

Methylcobalamin, a.k.a. methyl B-12 is a fat-soluble variation of cobalamin which has been considered as an effective supplement for neuropathy and nerve pain treatment. People who are deficient in Vitamin B-12 have reported muscle weakness, slow thinking, tingling, and numbness in the extremities, which may be why experts believe that this particular vitamin is essential in nerve health. Also, studies have shown that methyl B-12 provides protection and aid in the regeneration of myelin sheaths that play a critical role in nerve function.


Magnesium also considered as a useful supplement for people with neuropathy because of its properties that aid in nerve regeneration. While this claim has yet to be tested further through clinical research, many neuropathic doctors believe that magnesium is directly linked to nerve damage, especially in diabetic patients suffering from peripheral neuropathy. In fact, multiple studies have shown that diabetic patients experiencing nerve pain have lower levels of this mineral compared to those without neuropathic symptoms.